primary antibodies against adamts-5 Search Results


human adamts5 duoset elisa  (Bio-Techne corporation)
93
Bio-Techne corporation human adamts5 duoset elisa
Human Adamts5 Duoset Elisa, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human adamts5 duoset elisa/product/Bio-Techne corporation
Average 93 stars, based on 1 article reviews
human adamts5 duoset elisa - by Bioz Stars, 2026-03
93/100 stars
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polyclonal antibodies  (Bioss)
94
Bioss polyclonal antibodies
ERp57 cKO mice show an accelerated development of osteoarthritis during aging. ( A ) Histological analysis and OARSI scoring of toluidine blue-stained knee sections of 18-month-old mice reveals an increase in cartilage degradation, the occurrence of hypertrophic chondrocytes (*), and osteophyte formation (scattered box) in ERp57 cKO mice, but not in WT animals ( p = 0.0039). No significant difference was detected between younger WT and ERp57 cKO mice at the age of 9 months ( p = 0.7924) and 12 months ( p = 0.2503). Scale Bars = 100 µm. ( B ) TUNEL staining indicates a higher percentage of apoptotic cells in the articular cartilage of ERp57 cKO mice at 9 ( p = 0.0271), 12 ( p = 0.0490) and 18 months ( p = 0,000000028) compared to WT animals. Scale bars = 50 µm ( C ) Immunofluorescence of 18-month-old ERp57 cKO cartilage reveals increased staining intensities of matrix degrading proteases MMP3 ( p = 0.0004), MMP9 ( p = 0.0097), <t>ADAMTS4</t> ( p = 0.0428), and <t>ADAMTS5</t> ( p = 0.0288) compared to WT controls. M = months. n ≥ 4. *** p < 0.005, ** p < 0.01, * p < 0.05.
Polyclonal Antibodies, supplied by Bioss, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/polyclonal antibodies/product/Bioss
Average 94 stars, based on 1 article reviews
polyclonal antibodies - by Bioz Stars, 2026-03
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anti-adamts5 antibody picoband  (Boster Bio)
93
Boster Bio anti-adamts5 antibody picoband
ERp57 cKO mice show an accelerated development of osteoarthritis during aging. ( A ) Histological analysis and OARSI scoring of toluidine blue-stained knee sections of 18-month-old mice reveals an increase in cartilage degradation, the occurrence of hypertrophic chondrocytes (*), and osteophyte formation (scattered box) in ERp57 cKO mice, but not in WT animals ( p = 0.0039). No significant difference was detected between younger WT and ERp57 cKO mice at the age of 9 months ( p = 0.7924) and 12 months ( p = 0.2503). Scale Bars = 100 µm. ( B ) TUNEL staining indicates a higher percentage of apoptotic cells in the articular cartilage of ERp57 cKO mice at 9 ( p = 0.0271), 12 ( p = 0.0490) and 18 months ( p = 0,000000028) compared to WT animals. Scale bars = 50 µm ( C ) Immunofluorescence of 18-month-old ERp57 cKO cartilage reveals increased staining intensities of matrix degrading proteases MMP3 ( p = 0.0004), MMP9 ( p = 0.0097), <t>ADAMTS4</t> ( p = 0.0428), and <t>ADAMTS5</t> ( p = 0.0288) compared to WT controls. M = months. n ≥ 4. *** p < 0.005, ** p < 0.01, * p < 0.05.
Anti Adamts5 Antibody Picoband, supplied by Boster Bio, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti-adamts5 antibody picoband/product/Boster Bio
Average 93 stars, based on 1 article reviews
anti-adamts5 antibody picoband - by Bioz Stars, 2026-03
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adamts5 antibody  (Bio-Techne corporation)
94
Bio-Techne corporation adamts5 antibody
ERp57 cKO mice show an accelerated development of osteoarthritis during aging. ( A ) Histological analysis and OARSI scoring of toluidine blue-stained knee sections of 18-month-old mice reveals an increase in cartilage degradation, the occurrence of hypertrophic chondrocytes (*), and osteophyte formation (scattered box) in ERp57 cKO mice, but not in WT animals ( p = 0.0039). No significant difference was detected between younger WT and ERp57 cKO mice at the age of 9 months ( p = 0.7924) and 12 months ( p = 0.2503). Scale Bars = 100 µm. ( B ) TUNEL staining indicates a higher percentage of apoptotic cells in the articular cartilage of ERp57 cKO mice at 9 ( p = 0.0271), 12 ( p = 0.0490) and 18 months ( p = 0,000000028) compared to WT animals. Scale bars = 50 µm ( C ) Immunofluorescence of 18-month-old ERp57 cKO cartilage reveals increased staining intensities of matrix degrading proteases MMP3 ( p = 0.0004), MMP9 ( p = 0.0097), <t>ADAMTS4</t> ( p = 0.0428), and <t>ADAMTS5</t> ( p = 0.0288) compared to WT controls. M = months. n ≥ 4. *** p < 0.005, ** p < 0.01, * p < 0.05.
Adamts5 Antibody, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/adamts5 antibody/product/Bio-Techne corporation
Average 94 stars, based on 1 article reviews
adamts5 antibody - by Bioz Stars, 2026-03
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a synthesized peptide derived from human adamts5  (ImmunoGen Inc)
90
ImmunoGen Inc a synthesized peptide derived from human adamts5
ERp57 cKO mice show an accelerated development of osteoarthritis during aging. ( A ) Histological analysis and OARSI scoring of toluidine blue-stained knee sections of 18-month-old mice reveals an increase in cartilage degradation, the occurrence of hypertrophic chondrocytes (*), and osteophyte formation (scattered box) in ERp57 cKO mice, but not in WT animals ( p = 0.0039). No significant difference was detected between younger WT and ERp57 cKO mice at the age of 9 months ( p = 0.7924) and 12 months ( p = 0.2503). Scale Bars = 100 µm. ( B ) TUNEL staining indicates a higher percentage of apoptotic cells in the articular cartilage of ERp57 cKO mice at 9 ( p = 0.0271), 12 ( p = 0.0490) and 18 months ( p = 0,000000028) compared to WT animals. Scale bars = 50 µm ( C ) Immunofluorescence of 18-month-old ERp57 cKO cartilage reveals increased staining intensities of matrix degrading proteases MMP3 ( p = 0.0004), MMP9 ( p = 0.0097), <t>ADAMTS4</t> ( p = 0.0428), and <t>ADAMTS5</t> ( p = 0.0288) compared to WT controls. M = months. n ≥ 4. *** p < 0.005, ** p < 0.01, * p < 0.05.
A Synthesized Peptide Derived From Human Adamts5, supplied by ImmunoGen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/a synthesized peptide derived from human adamts5/product/ImmunoGen Inc
Average 90 stars, based on 1 article reviews
a synthesized peptide derived from human adamts5 - by Bioz Stars, 2026-03
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rabbit anti-adamts5 rp1a damts-5  (Triple Point Biologics)
90
Triple Point Biologics rabbit anti-adamts5 rp1a damts-5
ERp57 cKO mice show an accelerated development of osteoarthritis during aging. ( A ) Histological analysis and OARSI scoring of toluidine blue-stained knee sections of 18-month-old mice reveals an increase in cartilage degradation, the occurrence of hypertrophic chondrocytes (*), and osteophyte formation (scattered box) in ERp57 cKO mice, but not in WT animals ( p = 0.0039). No significant difference was detected between younger WT and ERp57 cKO mice at the age of 9 months ( p = 0.7924) and 12 months ( p = 0.2503). Scale Bars = 100 µm. ( B ) TUNEL staining indicates a higher percentage of apoptotic cells in the articular cartilage of ERp57 cKO mice at 9 ( p = 0.0271), 12 ( p = 0.0490) and 18 months ( p = 0,000000028) compared to WT animals. Scale bars = 50 µm ( C ) Immunofluorescence of 18-month-old ERp57 cKO cartilage reveals increased staining intensities of matrix degrading proteases MMP3 ( p = 0.0004), MMP9 ( p = 0.0097), <t>ADAMTS4</t> ( p = 0.0428), and <t>ADAMTS5</t> ( p = 0.0288) compared to WT controls. M = months. n ≥ 4. *** p < 0.005, ** p < 0.01, * p < 0.05.
Rabbit Anti Adamts5 Rp1a Damts 5, supplied by Triple Point Biologics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/rabbit anti-adamts5 rp1a damts-5/product/Triple Point Biologics
Average 90 stars, based on 1 article reviews
rabbit anti-adamts5 rp1a damts-5 - by Bioz Stars, 2026-03
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anti-adamts5 antibody pa5-14350  (Thermo Fisher)
90
Thermo Fisher anti-adamts5 antibody pa5-14350
ERp57 cKO mice show an accelerated development of osteoarthritis during aging. ( A ) Histological analysis and OARSI scoring of toluidine blue-stained knee sections of 18-month-old mice reveals an increase in cartilage degradation, the occurrence of hypertrophic chondrocytes (*), and osteophyte formation (scattered box) in ERp57 cKO mice, but not in WT animals ( p = 0.0039). No significant difference was detected between younger WT and ERp57 cKO mice at the age of 9 months ( p = 0.7924) and 12 months ( p = 0.2503). Scale Bars = 100 µm. ( B ) TUNEL staining indicates a higher percentage of apoptotic cells in the articular cartilage of ERp57 cKO mice at 9 ( p = 0.0271), 12 ( p = 0.0490) and 18 months ( p = 0,000000028) compared to WT animals. Scale bars = 50 µm ( C ) Immunofluorescence of 18-month-old ERp57 cKO cartilage reveals increased staining intensities of matrix degrading proteases MMP3 ( p = 0.0004), MMP9 ( p = 0.0097), <t>ADAMTS4</t> ( p = 0.0428), and <t>ADAMTS5</t> ( p = 0.0288) compared to WT controls. M = months. n ≥ 4. *** p < 0.005, ** p < 0.01, * p < 0.05.
Anti Adamts5 Antibody Pa5 14350, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti-adamts5 antibody pa5-14350/product/Thermo Fisher
Average 90 stars, based on 1 article reviews
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aryl thioxothiazolidinone adamts-5 inhibitor  (Millipore)
90
Millipore aryl thioxothiazolidinone adamts-5 inhibitor
ERp57 cKO mice show an accelerated development of osteoarthritis during aging. ( A ) Histological analysis and OARSI scoring of toluidine blue-stained knee sections of 18-month-old mice reveals an increase in cartilage degradation, the occurrence of hypertrophic chondrocytes (*), and osteophyte formation (scattered box) in ERp57 cKO mice, but not in WT animals ( p = 0.0039). No significant difference was detected between younger WT and ERp57 cKO mice at the age of 9 months ( p = 0.7924) and 12 months ( p = 0.2503). Scale Bars = 100 µm. ( B ) TUNEL staining indicates a higher percentage of apoptotic cells in the articular cartilage of ERp57 cKO mice at 9 ( p = 0.0271), 12 ( p = 0.0490) and 18 months ( p = 0,000000028) compared to WT animals. Scale bars = 50 µm ( C ) Immunofluorescence of 18-month-old ERp57 cKO cartilage reveals increased staining intensities of matrix degrading proteases MMP3 ( p = 0.0004), MMP9 ( p = 0.0097), <t>ADAMTS4</t> ( p = 0.0428), and <t>ADAMTS5</t> ( p = 0.0288) compared to WT controls. M = months. n ≥ 4. *** p < 0.005, ** p < 0.01, * p < 0.05.
Aryl Thioxothiazolidinone Adamts 5 Inhibitor, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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recombinant adamts5  (Wyeth Biopharma)
90
Wyeth Biopharma recombinant adamts5
ERp57 cKO mice show an accelerated development of osteoarthritis during aging. ( A ) Histological analysis and OARSI scoring of toluidine blue-stained knee sections of 18-month-old mice reveals an increase in cartilage degradation, the occurrence of hypertrophic chondrocytes (*), and osteophyte formation (scattered box) in ERp57 cKO mice, but not in WT animals ( p = 0.0039). No significant difference was detected between younger WT and ERp57 cKO mice at the age of 9 months ( p = 0.7924) and 12 months ( p = 0.2503). Scale Bars = 100 µm. ( B ) TUNEL staining indicates a higher percentage of apoptotic cells in the articular cartilage of ERp57 cKO mice at 9 ( p = 0.0271), 12 ( p = 0.0490) and 18 months ( p = 0,000000028) compared to WT animals. Scale bars = 50 µm ( C ) Immunofluorescence of 18-month-old ERp57 cKO cartilage reveals increased staining intensities of matrix degrading proteases MMP3 ( p = 0.0004), MMP9 ( p = 0.0097), <t>ADAMTS4</t> ( p = 0.0428), and <t>ADAMTS5</t> ( p = 0.0288) compared to WT controls. M = months. n ≥ 4. *** p < 0.005, ** p < 0.01, * p < 0.05.
Recombinant Adamts5, supplied by Wyeth Biopharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
recombinant adamts5 - by Bioz Stars, 2026-03
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gene exp adamts5 mm00478620 m1  (Thermo Fisher)
98
Thermo Fisher gene exp adamts5 mm00478620 m1
ERp57 cKO mice show an accelerated development of osteoarthritis during aging. ( A ) Histological analysis and OARSI scoring of toluidine blue-stained knee sections of 18-month-old mice reveals an increase in cartilage degradation, the occurrence of hypertrophic chondrocytes (*), and osteophyte formation (scattered box) in ERp57 cKO mice, but not in WT animals ( p = 0.0039). No significant difference was detected between younger WT and ERp57 cKO mice at the age of 9 months ( p = 0.7924) and 12 months ( p = 0.2503). Scale Bars = 100 µm. ( B ) TUNEL staining indicates a higher percentage of apoptotic cells in the articular cartilage of ERp57 cKO mice at 9 ( p = 0.0271), 12 ( p = 0.0490) and 18 months ( p = 0,000000028) compared to WT animals. Scale bars = 50 µm ( C ) Immunofluorescence of 18-month-old ERp57 cKO cartilage reveals increased staining intensities of matrix degrading proteases MMP3 ( p = 0.0004), MMP9 ( p = 0.0097), <t>ADAMTS4</t> ( p = 0.0428), and <t>ADAMTS5</t> ( p = 0.0288) compared to WT controls. M = months. n ≥ 4. *** p < 0.005, ** p < 0.01, * p < 0.05.
Gene Exp Adamts5 Mm00478620 M1, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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anti adamts5  (Danaher Inc)
86
Danaher Inc anti adamts5
ERp57 cKO mice show an accelerated development of osteoarthritis during aging. ( A ) Histological analysis and OARSI scoring of toluidine blue-stained knee sections of 18-month-old mice reveals an increase in cartilage degradation, the occurrence of hypertrophic chondrocytes (*), and osteophyte formation (scattered box) in ERp57 cKO mice, but not in WT animals ( p = 0.0039). No significant difference was detected between younger WT and ERp57 cKO mice at the age of 9 months ( p = 0.7924) and 12 months ( p = 0.2503). Scale Bars = 100 µm. ( B ) TUNEL staining indicates a higher percentage of apoptotic cells in the articular cartilage of ERp57 cKO mice at 9 ( p = 0.0271), 12 ( p = 0.0490) and 18 months ( p = 0,000000028) compared to WT animals. Scale bars = 50 µm ( C ) Immunofluorescence of 18-month-old ERp57 cKO cartilage reveals increased staining intensities of matrix degrading proteases MMP3 ( p = 0.0004), MMP9 ( p = 0.0097), <t>ADAMTS4</t> ( p = 0.0428), and <t>ADAMTS5</t> ( p = 0.0288) compared to WT controls. M = months. n ≥ 4. *** p < 0.005, ** p < 0.01, * p < 0.05.
Anti Adamts5, supplied by Danaher Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti adamts5/product/Danaher Inc
Average 86 stars, based on 1 article reviews
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anti-adamts5  (Affinity Biosciences)
90
Affinity Biosciences anti-adamts5
ERp57 cKO mice show an accelerated development of osteoarthritis during aging. ( A ) Histological analysis and OARSI scoring of toluidine blue-stained knee sections of 18-month-old mice reveals an increase in cartilage degradation, the occurrence of hypertrophic chondrocytes (*), and osteophyte formation (scattered box) in ERp57 cKO mice, but not in WT animals ( p = 0.0039). No significant difference was detected between younger WT and ERp57 cKO mice at the age of 9 months ( p = 0.7924) and 12 months ( p = 0.2503). Scale Bars = 100 µm. ( B ) TUNEL staining indicates a higher percentage of apoptotic cells in the articular cartilage of ERp57 cKO mice at 9 ( p = 0.0271), 12 ( p = 0.0490) and 18 months ( p = 0,000000028) compared to WT animals. Scale bars = 50 µm ( C ) Immunofluorescence of 18-month-old ERp57 cKO cartilage reveals increased staining intensities of matrix degrading proteases MMP3 ( p = 0.0004), MMP9 ( p = 0.0097), <t>ADAMTS4</t> ( p = 0.0428), and <t>ADAMTS5</t> ( p = 0.0288) compared to WT controls. M = months. n ≥ 4. *** p < 0.005, ** p < 0.01, * p < 0.05.
Anti Adamts5, supplied by Affinity Biosciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti-adamts5/product/Affinity Biosciences
Average 90 stars, based on 1 article reviews
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Image Search Results


ERp57 cKO mice show an accelerated development of osteoarthritis during aging. ( A ) Histological analysis and OARSI scoring of toluidine blue-stained knee sections of 18-month-old mice reveals an increase in cartilage degradation, the occurrence of hypertrophic chondrocytes (*), and osteophyte formation (scattered box) in ERp57 cKO mice, but not in WT animals ( p = 0.0039). No significant difference was detected between younger WT and ERp57 cKO mice at the age of 9 months ( p = 0.7924) and 12 months ( p = 0.2503). Scale Bars = 100 µm. ( B ) TUNEL staining indicates a higher percentage of apoptotic cells in the articular cartilage of ERp57 cKO mice at 9 ( p = 0.0271), 12 ( p = 0.0490) and 18 months ( p = 0,000000028) compared to WT animals. Scale bars = 50 µm ( C ) Immunofluorescence of 18-month-old ERp57 cKO cartilage reveals increased staining intensities of matrix degrading proteases MMP3 ( p = 0.0004), MMP9 ( p = 0.0097), ADAMTS4 ( p = 0.0428), and ADAMTS5 ( p = 0.0288) compared to WT controls. M = months. n ≥ 4. *** p < 0.005, ** p < 0.01, * p < 0.05.

Journal: International Journal of Molecular Sciences

Article Title: ER Stress in ERp57 Knockout Knee Joint Chondrocytes Induces Osteoarthritic Cartilage Degradation and Osteophyte Formation

doi: 10.3390/ijms23010182

Figure Lengend Snippet: ERp57 cKO mice show an accelerated development of osteoarthritis during aging. ( A ) Histological analysis and OARSI scoring of toluidine blue-stained knee sections of 18-month-old mice reveals an increase in cartilage degradation, the occurrence of hypertrophic chondrocytes (*), and osteophyte formation (scattered box) in ERp57 cKO mice, but not in WT animals ( p = 0.0039). No significant difference was detected between younger WT and ERp57 cKO mice at the age of 9 months ( p = 0.7924) and 12 months ( p = 0.2503). Scale Bars = 100 µm. ( B ) TUNEL staining indicates a higher percentage of apoptotic cells in the articular cartilage of ERp57 cKO mice at 9 ( p = 0.0271), 12 ( p = 0.0490) and 18 months ( p = 0,000000028) compared to WT animals. Scale bars = 50 µm ( C ) Immunofluorescence of 18-month-old ERp57 cKO cartilage reveals increased staining intensities of matrix degrading proteases MMP3 ( p = 0.0004), MMP9 ( p = 0.0097), ADAMTS4 ( p = 0.0428), and ADAMTS5 ( p = 0.0288) compared to WT controls. M = months. n ≥ 4. *** p < 0.005, ** p < 0.01, * p < 0.05.

Article Snippet: Then the Vectastain ® Elite ABC Universal Kit (VEC-PK-7200, BIOZOL, Eching, Germany) and the Vector ® DAB Peroxidase Substrate (VEC-SK-4100, BIOZOL, Eching, Germany) were used according to the manufacturer’s instructions with polyclonal antibodies (anti-ADAMTS4: bs-4191R, Bioss Antibodies Inc., Woburn, MA, USA, 1:200 and ADAMTS5: bs-3573R, Bioss Antibodies Inc, Woburn, MA, USA, 1:50), which were incubated on the slides overnight at 4 °C.

Techniques: Staining, TUNEL Assay, Immunofluorescence

ER stress-induced osteoarthritic changes in the knee joint. Knee joints of aged ERp57 cKO animals display severe OA cartilage degeneration with enhanced MMP3, MMP9, ADAMTS4, and ADAMTS5 expression and osteophyte formation. These changes are preceded by reduced compressive stiffness of the cartilage ECM and increased apoptotic cell death. Both effects are likely induced by ER stress that cannot be adequately compensated by the UPR.

Journal: International Journal of Molecular Sciences

Article Title: ER Stress in ERp57 Knockout Knee Joint Chondrocytes Induces Osteoarthritic Cartilage Degradation and Osteophyte Formation

doi: 10.3390/ijms23010182

Figure Lengend Snippet: ER stress-induced osteoarthritic changes in the knee joint. Knee joints of aged ERp57 cKO animals display severe OA cartilage degeneration with enhanced MMP3, MMP9, ADAMTS4, and ADAMTS5 expression and osteophyte formation. These changes are preceded by reduced compressive stiffness of the cartilage ECM and increased apoptotic cell death. Both effects are likely induced by ER stress that cannot be adequately compensated by the UPR.

Article Snippet: Then the Vectastain ® Elite ABC Universal Kit (VEC-PK-7200, BIOZOL, Eching, Germany) and the Vector ® DAB Peroxidase Substrate (VEC-SK-4100, BIOZOL, Eching, Germany) were used according to the manufacturer’s instructions with polyclonal antibodies (anti-ADAMTS4: bs-4191R, Bioss Antibodies Inc., Woburn, MA, USA, 1:200 and ADAMTS5: bs-3573R, Bioss Antibodies Inc, Woburn, MA, USA, 1:50), which were incubated on the slides overnight at 4 °C.

Techniques: Expressing